A Study On Turner Syndrome - 1724 Words

Turner syndrome, also known as Monosomy X, is caused by the deletion of the second X chromosome in females. This can be a partial deletion or a complete deletion. It is caused by a random error called nondisjunction, which is â€Å"the failure of sister chromatids to separate during or after meiosis† (Biology Online, 2008). This can lead to an abnormal amount of chromosomes. In this case, it leads to an abnormality in the sex chromosomes leaving the woman with one functioning X chromosome. While the specific genes that cause Turner syndrome are unknown, researchers â€Å"have identified one gene called SHOX that is important for bone development and growth† (National Library of Medicine, 2013). It is believed that a missing SHOX gene is the reason behind the female’s short stature and skeletal abnormalities. Due to the random nature of this syndrome, it is usually not inherited or passed down. The loss or mutation of the X chromosome is spontaneous; therefore the re is no real pattern of inheritance. Also, it is very unlikely for a woman with Turner syndrome to pass it down to her daughter. Women with Turner syndrome have one functioning X chromosome. If the woman does become pregnant, she will only be able to pass down the functioning X to her child, meaning the daughter will not have Turner syndrome unless she goes through the same random mutation. According to the Turner Syndrome Society (2016), woman with Turner syndrome can experience signs and symptoms such as short stature, aShow MoreRelatedGenetic Disease : Turner Syndrome1104 Words   |  5 PagesIn 1938, Dr. Henry Turner first described Turner Syndrome. Turner Syndrome a genetic disease that only affects girls, in fact, it is one of the most common sexual development disorders (Radtke et al. 2014). It is caused by an abnormal sex chromosome, either an abnormal X chromosome or a missing X chromosome. The sex chromosome contributed by the father to the child determines the sex of th e child because the mother always contributes an X chromosome whereas the father can contribute either an X chromosomeRead MoreTurner Syndrome : A Chromosomal Disorder1165 Words   |  5 PagesTurner Syndrome Shinji Lin December 15, 2015 Period 5 Turner syndrome is a chromosomal disorder that affects development in females. This condition is caused by a missing or incomplete X chromosome. In 1938, Henry Turner, an American endocrinologist, described seven women with short stature, lack of sexual development, neck webbing (extra skin on neck), low hairline, and cubitus valgus (arms that turn out at the elbow). Years earlier, Otto Ullrich, a German geneticist, independently describedRead MoreTurner Syndrome, A Rare Medical Disorder1351 Words   |  6 PagesDysgenesis Gonadal Dysgenesis, also known as turner syndrome, is a rare medical disorder that affects 1 in every 2,500 girls (kidshealth). It is a chromosomal that occurs when one of the two X chromosomes found in females are missing or is incomplete. This condition only affects females. Although researches don’t know exactly what cause turner syndrome, they do know that it’s a problem with a female chromosome. Females who are born with Tuner Syndrome are short in height and effects their sexualRead More Turner syndrome Essay1096 Words   |  5 Pagesabnormalities. The Turner Syndrome (known as Ullrich-Turner Syndrome in Germany) is a congenital disease. A German doctor named Ullrich published his article in 1930. American doctor Henry Turner recognized a pattern of short stature and incomplete sexual maturation in otherwise normal females. He published a comprehensive medical description of the syndrome. It was not until 1959, that it became clear the syndrome was due to lack of sex chromosome material. 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Turner syndrome; 45,X) have a high prevalence of autoimmune diseases; especially early onset autoimmune thyroiditis.10,12 Approximately ~40% of these women have antibodies targeting the thyroid and their prevalence of autoimmun e thyroiditis is ~100 fold higher than men (46,XY) and ~17 fold higher than normal women (46,XX) (Figure 2a).1,3,10,12 Because Turner syndrome (45,X) women do not have an inactivated second X chromosome, theirRead MoreLanguage Perception961 Words   |  4 PagesHowever, Onishi and Baillargeon [2005] study finding that child’s carry out gaze for longer in this case which the infants sees the toy in an area that was contradictory with her own belief. But will this suggest that child’s do understand people false belief as stated by Onishi and Baillargeon? Moreover, the explanation of this research was an intense discussion. 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